Most of the Virus/Worm/Trojans which infect a windows system needs an invoker to run, so these viruses add then with the windows startup programs. So, they use Window registry or common startup to start on Windows logon and harm your computer.
DiStartup is a freeware tool which runs as a windows service that delete the Windows startup programs, and monitor the Windows registry and common startup in case of prevent and delete any program to enter the startup programs safety area.
As this program runs as a windows service, so it does not have any visible interface, This program runs as service which runs first before any running program, DiStartup runs and delete the startup programs before they will be runs.

Distartup monitor the following registry keys:
All Users-RunOnce
HKEY_LOCAL_MACHINE\Software\Microsoft\Windows\CurrentVersion\RunOnce
All Users-Run
HKEY_LOCAL_MACHINE\Software\Microsoft\Windows\CurrentVersion\Run
All Users-RunOnceEx
HKEY_LOCAL_MACHINE\Software\Microsoft\Windows\CurrentVersion\RunOnceEx
All Users-RunEx
HKEY_LOCAL_MACHINE\Software\Microsoft\Windows\CurrentVersion\RunEx
Current User-RunOnce
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\RunOnce
Current User-Run
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Run
Current User-RunOnceEx
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\RunOnceEx
Current User-RunEx
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\RunEx

Give Distartup a try to see what it’s all about!

DiStartup

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